Journal of Applied Nonlinear Dynamics
Impact of Vaccination and Awareness Campaign in Reducing Mpox Transmission: A Fractional Mathematical Study
Journal of Applied Nonlinear Dynamics 14(4) (2025) 847--857 | DOI:10.5890/JAND.2025.12.007
Jayanta Mondal$^1$, Samapti Mondal$^1$, Piu Samui$^2$
$^1$ Department of Mathematics, Diamond Harbour Women's University, Sarisha, West Bengal-743368, India
$^2$ Department of Mathematics, Swami Vivekananda University, Barrackpore, West Bengal-700121, India
Download Full Text PDF
Abstract
The 2022 - 2023 global Mpox outbreak is proclaimed as feasible pandemic by WHO. The present study addresses obscure epidemiological traits of intrahuman Mpox transmission through a deterministic four-dimensional model and its Caputo fractional-order counterpart in the context of memory. Stability conditions around both the infection-free equilibrium and the endemic equilibrium are established. The model is parameterized based on real Mpox data of 2022 - 2023 global outbreak in Nigeria. Numerical simulations are displaying the requirements of non-pharmaceutical and pharmaceutical interventions to control the Mpox transmission. Choosing effectiveness of awareness campaign and recovery rate through antiviral treatment as well as other precautionary measures as Hopf-bifurcation parameters, conditions for subcritical Hopf-bifurcation and supercritical Hopf-bifurcation carried out. Furthermore, the effectiveness of awareness campaign must be increased to upgrade the global Mpox vaccination uptake rate and to curb the potential contact among human beings in order to cut the Mpox transmission chain.
References
-
[1]  | WHO (2023), Mpox Key Facts, https://www.who.int/news-room/fact-sheets/detail/monkeypox/, Archived on May 21.
|
-
[2]  | CDC (2023), About Mpox, https://www.cdc.gov/poxvirus/mpox/about/, Archived on August 31.
|
-
[3]  | ECDC (2022), Epidemiological Update: Monkeypox Outbreak, https://www.ecdc.europa.eu/en/news-events/epidemiological-update-monkeypox-outbreak.
|
-
[4]  | WHO, Mpox (Monkeypox) Outbreak 2022 - Global, https://www.who.int/emergencies/situations/monkeypox-outbreak-2022, Retrieved on December 19.
|
-
[5]  | Sulaiman, U. and Ibrahim, I.A. (2017), Modeling the transmission dynamics of the monkeypox virus infection with treatment and vaccination interventions, Journal of Applied Mathematics and Physics, 5(12), 2335.
|
-
[6]  | Majee, S., Jana, S., and Kar, T.K. (2023), Dynamical analysis of monkeypox transmission incorporating optimal vaccination and treatment with cost-effectiveness, Chaos: An Interdisciplinary Journal of Nonlinear Science, 33(4).
|
-
[7]  | El-Mesady, A., Elsonbaty, A., and Adel, W. (2022), On nonlinear dynamics of a fractional order monkeypox virus model, Chaos, Solitons \& Fractals, 164, 112716.
|
-
[8]  | Peter, O.J., Kumar, S., Kumari, N., Oguntolu, F.A., Oshinubi, K., and Musa, R. (2022), Transmission dynamics of Monkeypox virus: a mathematical modelling approach, Modeling Earth Systems and Environment, 1-12.
|
-
[9]  | Adel, W., Elsonbaty, A., Aldurayhim, A., and El-Mesady, A. (2023), Investigating the dynamics of a novel fractional-order monkeypox epidemic model with optimal control, Alexandria Engineering Journal, 73, 519-542.
|
-
[10]  | Majee, S., Jana, S., Barman, S., and Kar, T.K. (2023), Transmission dynamics of monkeypox virus with treatment and vaccination controls: A fractional order mathematical approach, Physica Scripta, 98(2), 024002.
|
-
[11]  | Olaniyi, S. and Chuma, F.M. (2023), Lyapunov stability and economic analysis of Monkeypox dynamics with vertical transmission and vaccination, International Journal of Applied and Computational Mathematics, 9(5), 85.
|
-
[12]  | El-Mesady, A., Adel, W., Elsadany, A.A., and Elsonbaty, A. (2023), Stability analysis and optimal control strategies of a fractional-order monkeypox virus infection model, Physica Scripta, 98(9), 095256.
|
-
[13]  | Mondal, J., Khajanchi, S., and Samui, P. (2022), Impact of media awareness in mitigating the spread of an infectious disease with application to optimal control, European Physical Journal Plus, 137(8), 983.
|
-
[14]  | Peter, O.J., Oguntolu, F.A., Ojo, M.M., Olayinka, O.A., Jan, R., and Khan, I. (2022), Fractional order mathematical model of monkeypox transmission dynamics, Physica Scripta, 97(8), 084005.
|
-
[15]  | Bhunu, C.P. and Mushayabasa, S. (2011), Modelling the transmission dynamics of pox-like infections, International Journal of Applied Mathematics, 41(2).
|
-
[16]  | Li, H.L., Zhang, L., Hu, C., Jiang, Y.L., and Teng, Z. (2017), Dynamical analysis of a fractional-order predator-prey model incorporating a prey refuge, Journal of Applied Mathematics and Computing, 54, 435-449.
|
-
[17]  | Li, Y., Chen, Y., and Podlubny, I. (2010), Stability of fractional-order nonlinear dynamic systems: Lyapunov direct method and generalized Mittag-Leffler stability, Computers and Mathematics with Applications, 59(5), 1810-1821.
|
-
[18]  | Odibat, Z.M. and Shawagfeh, N.T. (2007), Generalized Taylor’s formula, Applied Mathematics and Computation, 186(1), 286-293.
|
-
[19]  | Diekmann, O., Heesterbeek, J.A.P., and Metz, J.A.J. (1990), On the definition and the computation of the basic reproduction ratio $R_0$ in models for infectious diseases in heterogeneous populations, Journal of Mathematical Biology, 28, 365-382.
|
-
[20]  | La Salle, J.P. (1976), The Stability of Dynamical Systems, SIAM.
|
-
[21]  | Greenhalgh, D. (1997), Hopf bifurcation in epidemic models with a latent period and nonpermanent immunity, Mathematical and Computer Modelling, 25(2), 85-107.
|
-
[22]  | Li, X. and Wu, R. (2014), Hopf bifurcation analysis of a new commensurate fractional-order hyperchaotic system, Nonlinear Dynamics, 78, 279-288.
|
-
[23]  | Zabidi, N.A., Majid, Z.A., Kilicman, A., and Ibrahim, Z.B. (2022), Numerical solution of fractional differential equations with Caputo derivative by using numerical fractional predict--correct technique, Advances in Continuous and Discrete Models, 2022(1), 26.
|